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Evidence Grading

UKS treats evidence quality as first-class and never collapses it to a boolean. Two independent, closed vocabularies travel with every source: an evidence grade and a clinical status.

Evidence grade (GRADE-aligned)

GradeMeaning
highMeta-analyses of RCTs
moderateIndividual RCTs with limitations
lowObservational / cohort studies
very_lowExpert opinion
n_aDatasets, non-clinical content

This mirrors the GRADE framework used in evidence-based medicine. It is a closed vocabulary — mis-grading evidence is a safety hazard, so new values require a minor version bump, not an ad-hoc extension.

Clinical status

StatusMeaning
validatedEstablished consensus / standard of care
emergingPromising, not yet replicated at scale
contestedActively disputed
commercialPrimarily marketing content
informationalFactual, non-clinical
n_aNot applicable

Clinical status is separate from evidence grade — a source can be high-grade and contested at the same time.

Why "contested" matters

Some claims are genuinely disputed, and flattening them to "true/false" is dangerous. For example, genotype-guided dosing for MTHFR / COMT / APOE must be marked contested, per ACMG guidance. The Registry enforces this at publish time: asserting such content as validated is rejected. The registry can also derive contestedness empirically from the corpus — see Trust & safety.

Licenses are never collapsed either

Every source carries both a license_label (e.g. "CC BY 4.0") and a rights_url. This pairing lets an agent make a correct reuse decision instead of guessing from a single boolean "open?" flag.

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